Perceives Failure
"If I'm put on insulin, I must be doing something wrong."
- Perceives Failure

Before insulin initiation, patients may have spent an average of about 5 years with an A1C >8% and nearly 10 years >7%4

You may want to have the insulin talk sooner

β-cell function can decline annually as disease advances.1,2

Patients with T2DM suffer from insulin deficiency long before diagnosis.1



Rethinkinsulin.com Rethinkinsulin.com Patients with T2DM suffer from insulin deficiency long before diagnosis

Many patients tend to view their diabetes as a personal failure. Sometimes despite attempted lifestyle modifications, and OAD regimens, blood glucose levels still remain uncontrolled. Patients might focus on blaming themselves, often unaware that their pancreas is no longer making enough insulin.3

For appropriate patients, starting insulin earlier in the disease continuum may be one way to gain blood glucose control.

  • Before insulin initiation, patients may have spent an average of about 5 years with an A1C >8% and nearly 10 years >7%4
  • At diagnosis, up to 50% of a patient's β-cell function may have been lost, and may continue to decline by about 5% annually1,2
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Important Safety Information for Lantus®

Contraindications

Lantus® is contraindicated in patients hypersensitive to insulin glargine or one of its excipients.

Warnings and precautions

Monitor blood glucose in all patients treated with insulin. Insulin regimens should be modified cautiously and only under medical supervision. Changes in insulin strength, manufacturer, type, or method of administration may result in the need for a change in insulin dose or an adjustment in concomitant oral antidiabetic treatment.

Do not dilute or mix Lantus® with any other insulin or solution. If mixed or diluted, the solution may become cloudy, and the onset of action/time to peak effect may be altered in an unpredictable manner. Do not administer Lantus® via an insulin pump or intravenously because severe hypoglycemia can occur. Insulin devices and needles must not be shared between patients.

Hypoglycemia is the most common adverse reaction of insulin therapy, including Lantus®, and may be life-threatening.

Severe life-threatening, generalized allergy, including anaphylaxis, can occur.

A reduction in the Lantus® dose may be required in patients with renal or hepatic impairment.

Drug interactions

Certain drugs may affect glucose metabolism, requiring insulin dose adjustment and close monitoring of blood glucose. The signs of hypoglycemia may be reduced in patients taking anti-adrenergic drugs (e.g., beta-blockers, clonidine, guanethidine, and reserpine).

Adverse reactions

Other adverse reactions commonly associated with Lantus® are injection site reaction, lipodystrophy, pruritus, and rash.

Important Safety Information for Lantus® SoloSTAR®

Lantus® SoloSTAR® is a disposable prefilled insulin pen. To help ensure an accurate dose each time, patients should follow all steps in the Instruction Leaflet accompanying the pen; otherwise they may not get the correct amount of insulin, which may affect their blood glucose.

Indications and Usage for Lantus®

Lantus® is a long-acting insulin analog indicated to improve glycemic control in adults and children (6 years and older) with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus. Lantus® should be administered once a day at the same time every day.

Important Limitations of Use: Lantus® is not recommended for the treatment of diabetic ketoacidosis. Use intravenous short-acting insulin instead.

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References: 1. Holman RR. Diabetes Res Clin Pract. 1998;40(suppl):S21-S25.
2. UK Prospective Diabetes Study Group. Diabetes. 1995;44:1249-1258.
3. Hirsch IB, Bergenstal RM, Parkin CG, Wright E Jr, Buse JB. Clin Diabetes. 2005;23(2):78-86.
4. Brown JB, Nichols GA, Perry A. Diabetes Care. 2004;27(7):1535-1540.